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Albumin-bilirubin score for predicting the in-hospital mortality of variceal bleeding in children with liver cirrhosis

Abstract

To compare the prognostic value of ALBI score, an alternative predictor of mortality in cirrhotic adults, with Child-Pugh and PELD scores in cirrhotic children with variceal bleeding. We analyzed the patients’ data using MedCalc software, and calculated area under the curves (AUC) of receiving-operator characteristic (ROC). All scores were higher in expired compared to survived patients (p<0.001). The AUC values for predicting mortality in all patients were ⁓0.879±0.04 for Child-Pugh and PELD scores and 0.733±0.06 for ALBI. The prognostic values in two subgroups of biliary atresia (BA) and those with other underlying diseases(non-BA) showed that in BA group, ALBI score with AUC of 0.607±0.102, p<0.29, had no significant difference between survived and non-survived patients. ALBI in non-BA group, with AUC of 0.863±0.063 showed closer value to other scores (⁓0.954), and was differed between survived and non-survived groups (p<0.001), suggesting that ALBI might be useful in predicting mortality in non-BA patients.

Keywords: Cirrhosis; ALBI; Child-Pugh, PELD; Biliary atresia
Copyright © 2022 Maryam Esmaeilbeig, Maryam Ataollahi, Seyed Mohsen Dehghani, Ashkan Nikaeen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.